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Product Specifications
MOTS-c is a mitochondria-derived peptide studied for its potential roles in metabolic regulation, energy homeostasis, and cellular resilience. Supplied in a 10mg lyophilized vial for laboratory research use only.
Requires reconstitution with bacteriostatic water (Sold Here)
$104.99
About this Peptide
Pharmaceutical-grade. ≥99% purity. For research use only.
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded by the mitochondrial genome, identified as a key player in metabolic stress response. Unlike nuclear-encoded peptides, MOTS-c is produced within the mitochondria and has been explored for its influence on cellular energy balance, insulin sensitivity, and mitochondrial biogenesis.
Current research has focused on MOTS-c’s potential mechanisms in:
This 10mg vial of MOTS-c is synthesized to ≥99% purity and lyophilized under sterile conditions to ensure molecular integrity for advanced in vitro investigations.
Storage & Handling: Store lyophilized peptide at -20°C. Once reconstituted with bacteriostatic water, refrigerate at 2–8°C and use within 30 days. For laboratory research use only. Not for human or animal administration.
Disclaimer: This material is intended solely for scientific research. It is not approved for diagnostic, therapeutic, or clinical use in humans or animals. Handle in accordance with institutional research standards.
Name
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)
Concentration
10mg per vial
Form
Lyophilized peptide powder
Purity
≥99%, confirmed by HPLC and MS
Packaging
Sterile, sealed vial
Storage
-20°C in a dark, dry environment
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondria-derived peptide encoded within the 12S ribosomal RNA gene of the mitochondrial genome. Unlike most peptides which are nuclear-encoded, MOTS-c is of mitochondrial origin, making it a unique subject of research into mitochondrial-nuclear communication, metabolic regulation, and cellular stress response pathways.
MOTS-c is investigated primarily in the context of metabolic homeostasis, insulin sensitivity, and mitochondrial bioenergetics. Research has explored its capacity to translocate to the nucleus under conditions of metabolic stress, where it is thought to regulate gene expression related to glucose metabolism, AMPK pathway activation, and cellular adaptation to oxidative stress — making it a compelling subject in aging biology and metabolic disease research models.
MOTS-c is supplied as a lyophilized powder to ensure stability during storage and shipping. Reconstitution should be performed in a sterile laboratory environment using bacteriostatic water as the preferred diluent for multi-dose research applications. The vial should be gently swirled after addition of the diluent and never shaken to preserve peptide structural integrity.
Lyophilized MOTS-c should be stored at -20°C in a controlled, light-protected environment prior to reconstitution. Once reconstituted, the solution should be kept refrigerated at 2–8°C and used within the recommended timeframe. To minimize degradation, researchers are advised to prepare aliquots prior to storage to avoid repeated freeze-thaw cycles.
