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IGF-1 LR3 – Receptor Grade

Product Specifications

  • Receptor Grade
  • Synthetic analog of insulin-like growth factor-1 (IGF-1)
  • Modified for extended half-life and increased potency in lab models
  • Studied in protein synthesis and cellular growth research
  • ≥99% purity, HPLC and MS verified
  • Lyophilized powder format with COA available

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg3) is a synthetic analogue of endogenous IGF-1 studied for its potential role in cellular proliferation, anabolic signaling, and insulin receptor substrate pathway modulation. Supplied in a 1mg lyophilized vial for laboratory research only.

Requires reconstitution with bacteriostatic water (Sold Here)

$179.99

SKU LIFE01MGIFG1L Category Tag Brand:

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About this Peptide

Information About IGF-1 LR3 – Receptor Grade

(Receptor Grade)

IGF-1 LR3 (Insulin-like Growth Factor 1 Long Arg3) is a synthetic peptide analog of naturally occurring IGF-1, engineered to extend its half-life and enhance its stability in laboratory models. Known for its structural modifications—specifically a substitution of arginine at position 3 and a 13-amino acid extension—IGF-1 LR3 is designed to resist binding proteins and increase bioavailability in research settings.

At Lifestyle Peptides, we supply high-purity, lab-validated IGF-1 LR3, ideal for scientific inquiry into cell growth, protein synthesis, and anabolic signaling pathways. Our compound is produced in cGMP-compliant environments, third-party tested, and available exclusively for qualified research use.


Why Researchers Study IGF-1 LR3

IGF-1 plays a critical role in cellular development and regeneration, particularly in response to growth hormone (GH)stimulation. The LR3 modification has been shown in animal and in vitro models to exhibit greater potency and a longer duration of activity compared to native IGF-1.

In preclinical studies, IGF-1 LR3 is explored for its influence on:

  • Muscle cell differentiation and hypertrophy modeling
  • Myoblast proliferation and protein expression
  • Glucose metabolism and insulin pathway activity
  • Cellular repair in musculoskeletal research models
  • Neuroprotective signaling and cognitive model development

The extended half-life of IGF-1 LR3—up to 20-30 hours—makes it a valuable tool in research examining sustained receptor activation and signaling cascade analysis.

Each batch is tested for identity, purity, and stability to ensure quality for controlled research environments.


Compliance Notice

IGF-1 LR3 is a research chemical. It is not approved by the FDA and is not intended for human or veterinary use. This compound must not be consumed, injected, applied topically, or used for therapeutic or diagnostic purposes. It is provided solely for non-clinical research by qualified professionals.

For laboratory research use only. Not for human or animal consumption.

Product specifications

Name

IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1)

Concentration

1mg per vial

Form

Lyophilized peptide powder

Purity

≥99%, confirmed by HPLC and MS

Storage

-20°C in a dark, dry environment

Packaging

Sterile, sealed vial

Documentation

Certificate of Analysis (COA) available upon request

FAQs

Frequently Asked Questions

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg³) is a synthetic analog of native IGF-1. It features a 13-amino-acid N-terminal extension plus an arginine substitution at position 3, modifications that markedly prolong half-life and reduce binding to IGF-binding proteins in laboratory models.

Because it binds less tightly to IGF-binding proteins and circulates longer, IGF-1 LR3 produces a more sustained activation of IGF-1 receptors in vitro and in animal studies. That extended window helps scientists probe downstream signalling—Akt/mTOR, protein-synthesis kinetics, and glucose-uptake pathways—without the rapid degradation seen with native IGF-1.

A medical prescription is not required because the peptide is not sold for therapeutic use. However, Lifestyle Peptides restricts sales to qualified researchers, laboratories, and institutions that agree to our terms of sale affirming laboratory-research-only intent and compliance with all applicable regulations.

Typical non-clinical applications include:

  • Skeletal-muscle hypertrophy and myoblast differentiation models
  • Akt/mTOR pathway mapping and protein-synthesis studies
  • Glucose-uptake and insulin-sensitivity assays
  • Comparative work on GH/IGF-1 axis regulation and tissue-repair kinetics

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